3,650 research outputs found

    Phosphorene-AsP Heterostructure as a Potential Excitonic Solar Cell Material - A First Principles Study

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    Solar energy conversion to produce electricity using photovoltaics is an emerging area in alternative energy research. Herein, we report on the basis of density functional calculations, phosphorene/AsP heterostructure could be a promising material for excitonic solar cells (XSCs). Our HSE06 functional calculations show that the band gap of both phosphorene and AsP fall exactly into the optimum value range according to XSCs requirement. The calculated effective mass of electrons and holes show anisotropic in nature with effective masses along Γ{\Gamma}-X direction is lower than the Γ{\Gamma}-Y direction and hence the charge transport will be faster along Γ{\Gamma}-X direction. The wide energy range of light absorption confirms the potential use of these materials for solar cell applications. Interestingly, phosphorene and AsP monolayer forms a type-II band alignment which will enhance the separation of photogenerated charge carriers and hence the recombination rate will be lower which can further improve its photo-conversion efficiency if one use it in XSCs

    The Gene Ontology: enhancements for 2011

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    The Gene Ontology (GO) (http://www.geneontology.org) is a community bioinformatics resource that represents gene product function through the use of structured, controlled vocabularies. The number of GO annotations of gene products has increased due to curation efforts among GO Consortium (GOC) groups, including focused literature-based annotation and ortholog-based functional inference. The GO ontologies continue to expand and improve as a result of targeted ontology development, including the introduction of computable logical definitions and development of new tools for the streamlined addition of terms to the ontology. The GOC continues to support its user community through the use of e-mail lists, social media and web-based resources

    Partial (13)C isotopic enrichment of nucleoside monophosphates: useful reporters for NMR structural studies

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    Analysis of the (13)C isotopic labeling patterns of nucleoside monophosphates (NMPs) extracted from Escherichia coli grown in a mixture of C-1 and C-2 glucose is presented. By comparing our results to previous observations on amino acids grown in similar media, we have been able to rationalize the labeling pattern based on the well-known biochemistry of nucleotide biosynthesis. Except for a few notable absences of label (C4 in purines and C3′ in ribose) and one highly enriched site (C1′ in ribose), most carbons are randomly enriched at a low level (an average of 13%). These sparsely labeled NMPs give less complex NMR spectra than their fully isotopically labeled analogs due to the elimination of most (13)C–(13)C scalar couplings. The spectral simplicity is particularly advantageous when working in ordered systems, as illustrated with guanosine diphosphate (GDP) bound to ADP ribosylation factor 1 (ARF1) aligned in a liquid crystalline medium. In this system, the absence of scalar couplings and additional long-range dipolar couplings significantly enhances signal to noise and resolution

    Generation of Werner states via collective decay of coherently driven atoms

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    We show deterministic generation of Werner states as a steady state of the collective decay dynamics of a pair of neutral atom coupled to a leaky cavity and strong coherent drive. We also show how the scheme can be extended to generate 2N2N-particle analogue of the bipartite Werner states.Comment: 4 pages, 1 figur

    Huntington's disease: An immune perspective

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    Copyright © 2011 Annapurna Nayaketal. This article has been made available through the Brunel Open Access Publishing Fund.Huntington's disease (HD) is a progressive neurodegenerative disorder that is caused by abnormal expansion of CAG trinucleotide repeats. Neuroinflammation is a typical feature of most neurodegenerative diseases that leads to an array of pathological changes within the affected areas in the brain. The neurodegeneration in HD is also caused by aberrant immune response in the presence of aggregated mutant huntingtin protein. The effects of immune activation in HD nervous system are a relatively unexplored area of research. This paper summarises immunological features associated with development and progression of HD.U. Kishore acknowledges funding via BRIEF and Brunel University’s strategic funding for the Centre of Infection, Immunity and Disease Mechanisms

    A case of auricular tuberculosis - Is it congenital or neonatal tuberculosis?

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    Tuberculosis (TB) in children is one of the leading infectious diseases worldwide and is still a serious public health problem in many countries. True congenital TB is rare; the greatest threat to the neonate is the acquisition of TB infection shortly before or after birth, which tends to progress rapidly to serious TB disease in a large proportion of untreated infants. The definition of congenital TB is so stringent that some cases of neonatal TB like the one we are reporting here lead to confusion as to whether we should report it as congenital TB or neonatal TB. We report an unusual case of localized auricular TB in a preterm neonate. Neonatal TB is rare but can be severe
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